Improvement in Cranioplasty: Advanced Prosthesis Biomanufacturing

Cranioplasty prosthesis manufacturing based on reverse engineering technology

BACKGROUND Most patients with large focal skull bone loss after craniectomy are referred for cranioplasty. Reverse engineering is a technology which creates a computer-aided design (CAD) model of a real structure. Rapid prototyping is a technology which produces physical objects from virtual CAD models. The aim of this study was to assess the clinical usefulness of these technologies in craniop...

Neurological improvement after cranioplasty - analysis by transcranial doppler ultrasonography.

Cranioplasty can improve neurological status in patients with skull bone defects. The mechanism of postoperative improvement in neurologic status might be increased cerebral blood flow (CBF) velocity due to elimination of the effects of atmospheric pressure. Between May 2001 and June 2002, 13 patients (8 men and 5 women; average age, 46 years; range, 21-65 years) were studied. Postoperative cha...

Biomanufacturing In Industrial Engineering

Biotechnology has become one of the primary technology development areas of the 21 century. For a medical device or pharmaceutical manufacturer to remain on the competitive edge, not only is it necessary to satisfy the stringent demands of the biotechnology markets, but those companies must also develop processes that can accelerate the time frame from research and development to manufacturing ...

A Case study of Performance Improvement of Femur Prosthesis

Nowadays, the placement of artificial prostheses in human skeleton, etc. is common due to different reasons such as fractures or deficiencies. Prostheses are structures that assist the performance of organs by reconstruction of some body parts through different methods to enable the organ to re-obtain its performance completely or partially and, since the use of external prostheses might lead t...

Biomanufacturing : time for change ?